Congratulations to Dr. Manish Sadarangani and the BOBBi Research Team!

POPCORN is proud to share that Better Outcomes in Babies with Bacterial meningitis (BOBBi), a randomized controlled trial led by Dr. Manish Sadarangani (Nominated Principal Applicant) and Dr. Caroline Quach-Thanh (Principal Applicant), has been awarded a five-year project grant from the Canadian Institutes of Health Research (CIHR). The study will be conducted at 14 pediatric sites across our research platform, with additional funding to support 60 trial sites in the United Kingdom.

Acute bacterial meningitis (ABM) is a life-threatening infection that often affects infants under three months old, frequently leading to death or long-term disabilities such as hearing or vision loss, seizures, and other serious neurodevelopmental impairments.

While steroids like dexamethasone are recommended for older children with certain forms of ABM, there is little high-quality evidence to guide treatment for infants. The BOBBi trial will address this gap, investigating whether steroids can improve outcomes for this vulnerable age group.

Congratulations to Dr. Sadarangani and the entire BOBBi team for advancing critical research to improve pediatric care worldwide!